45+
Human Clinical Studies on Niagen® NR

I'm careful about what goes in my body. Supporting myself at the cellular level with Tru Niagen is how I can keep doing what I love.
Kelly Slater
11 World Surf League (WSL) World Championship
From your daily routine to your biggest goals, Tru Niagen powers your cellular health, helping you thrive.
Replenish NAD+ daily to keep your cells energized, supported during repair, and resilient.
Supports cellular energy that your heart cells need.
Help fuel your muscle cells to supports muscle cells at a cellular level.
Support your 37.2 trillion cells by supporting cellular energy, metabolism, and repair.
Daily stressors can deplete NAD+, which can accelerate aging. Replenish NAD+ to support your health.
Niagen® is supported by 45+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 75% of published peer-reviewed clinical studies on NR use Niagen® NR.
Partnership with 300+ institutions: We partner with top institutions like Mayo Clinic, National Institute on Aging, Harvard, and Cambridge.
Backed by independent research: Over 90% of peer-reviewed, published Niagen® studies are investigator-driven and third-party funded.
From the NAD+ authority trusted by physicians, athletes, researchers, and a Nobel Prize-winning biochemist.
45+
Human Clinical Studies on Niagen® NR
60+
Proprietary NR Patents
500+
Published Scientific Studies
300+
Global Research Collaborations
Effortless routines. Research-backed cellular support.
NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every cell of your body that powers hundreds of metabolic processes. It serves as a key player in cellular energy production, DNA repair, and cellular communication. NAD+ works by transferring electrons during cellular metabolism, enabling your cells to convert nutrients into energy and supporting essential functions that keep your body running optimally.
NAD+ levels naturally decline from birth, accelerating around age 30, and dropping by up to 65% by age 70. Environmental and lifestyle stressors also diminish NAD+ levels, as do immune and health challenges. Taking a clinically proven supplement like Tru Niagen helps maintain your NAD+ baseline levels with daily use—to keep your body running smoothly as you age.
Tru Niagen is a superior choice compared to other NAD supplements because it contains Niagen®, our patented nicotinamide riboside (NR), a more bioavailable precursor to NAD+. Niagen® NR is backed by 45+ human clinical studies, and crosses cell membranes easily and is more efficiently converted into NAD+ inside cells, effectively boosting NAD+ levels.
This enhances energy metabolism, supports cellular repair, and promotes healthy aging, making Tru Niagen a more reliable, high-quality, pure, and potent option for raising NAD+ compared to other supplements. Tru Niagen® is clinically shown to increase NAD+ levels by over 50% with 300mg daily and by up to 150% with 1000mg daily and is backed by third-party quality-testing from NSF Certified for Sport and Alkemist Labs.
Cellular NAD+ support begins immediately upon supplementation. However, the cellular health benefits of increased NAD+ levels begin immediately, even before you feel noticeable changes.
Tru Niagen begins elevating NAD+ levels within hours of taking your first dose, with significant increases observed within 2 weeks of daily supplementation. For optimal results, we recommend taking Tru Niagen consistently as part of your daily routine.
Tru Niagen has been rigorously tested for safety and is well-tolerated. Our proprietary key ingredient Niagen® has successfully completed multiple FDA safety reviews and is manufactured in cGMP-certified facilities in the USA.
Niagen is supported by 45+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 75% of published peer-reviewed clinical studies on NR use Niagen® NR. Niagen is also backed by independent research, with over 90% of Niagen studies being investigator-driven and third-party funded.
In clinical studies, participants reported minimal to no side effects when taking the recommended dosage up to 2,000mg per day. Some individuals may experience mild and temporary effects that typically resolve quickly. As with any supplement, we recommend consulting with your healthcare provider before starting Tru Niagen, especially if you have existing health conditions or take medications.